Statistics of nascent and mature RNA fluctuations in a stochastic model of transcriptional initiation, elongation, pausing, and termination

DOI10.1007/S11538-020-00827-7MaRDI QIDQ2659780zbMATH OpenOpenAlexWikidataFDO

Authors Tatiana Filatova, Ramon Grima, Nikola Popović

Publication date 26 March 2021

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1007/s11538-020-00827-7

zbMATH Keywords

distributions of RNA moleculesmaster equationRNA fluctuationssingular perturbation theorystochastic gene expressionstochastic simulations

Mathematics Subject Classification ID

Applications of stochastic analysis (to PDEs, etc.) (60H30) Biochemistry, molecular biology (92C40)

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Cites work

• A geometric analysis of fast-slow models for stochastic gene expression
• Geometric singular perturbation theory for ordinary differential equations
• scientific article; zbMATH DE number 799793 (Why is no real title available?)
• Markovian modelling of gene product synthesis
• Parameter estimation for biochemical reaction networks using Wasserstein distances
• Solving the chemical master equation for monomolecular reaction systems analytically
• Time-dependent propagators for stochastic models of gene expression: an analytical method

Cited in

(10)

• Stochastic transcription elongation via rule based modelling
• Modulation of nuclear and cytoplasmic mRNA fluctuations by time-dependent stimuli: analytical distributions
• Stochastic kinetics description of a simple transcription model
• The influence of look-ahead on the error rate of transcription
• RNA Pol II transcription model and interpretation of GRO-seq data
• On the distribution of transcription times
• A Markovian arrival stream approach to stochastic gene expression in cells
• Assessing Markovian and delay models for single-nucleus RNA sequencing
• Quantitative modeling of the function of kinetically driven transcriptional riboswitches
• Estimation of kinetic parameters of transcription from temporal single-RNA measurements

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• DLMF

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