Test for rare variants by environment interactions in sequencing association studies

DOI10.1111/BIOM.12368zbMATH Open1393.62124OpenAlexW1485436594WikidataQ36522128 ScholiaQ36522128MaRDI QIDQ2805191FDOQ2805191

Authors: Xinyi Lin, Seunggeun Lee, Michael C. Wu, Chaolong Wang, Han Chen, Zilin Li, Xihong Lin 

Publication date: 10 May 2016

Published in: Biometrics (Search for Journal in Brave)

Full work available at URL: http://europepmc.org/articles/pmc4733434

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zbMATH Keywords

bias analysisgene-environment interactionssequencing association studies

Mathematics Subject Classification ID

Applications of statistics to environmental and related topics (62P12) Protein sequences, DNA sequences (92D20)

Cited In (12)

• A regularization-based adaptive test for high-dimensional GLMs
• Rare variant testing across methods and thresholds using the multi-kernel sequence kernel association test (MK-SKAT)
• A Cross-Validated Ensemble Approach to Robust Hypothesis Testing of Continuous Nonlinear Interactions: Application to Nutrition-Environment Studies
• Using ascertainment for targeted resequencing to increase power to identify causal variants
• Analysis of sequence data under multivariate trait-dependent sampling
• A powerful and data-adaptive test for rare-variant-based gene-environment interaction analysis
• A unified method for rare variant analysis of gene-environment interactions
• Ridge-penalized adaptive mantel test and its application in imaging genetics
• Omnibus testing approach for gene-based gene-gene interaction
• TFisher: a powerful truncation and weighting procedure for combining \(p\)-values
• Detecting rare and common haplotype-environment interaction under uncertainty of gene-environment independence assumption
• Likelihood ratio and score burden tests for detecting disease-associated rare variants

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