Detecting rare and common haplotype-environment interaction under uncertainty of gene-environment independence assumption

DOI10.1111/BIOM.12567MaRDI QIDQ5347448zbMATH OpenOpenAlexWikidataFDO

Authors Yuan Zhang, Shili Lin, Swati Biswas

Publication date 23 May 2017

Published in Biometrics (Search for Journal in Brave)

Full work available at URL http://europepmc.org/articles/pmc5288316

zbMATH Keywords

rare variantsMarkov chain Monte Carlo methodreversible jump MCMCmissing heritabilitygene-environment interactions (GXE)

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Protein sequences, DNA sequences (92D20)

Recommendations

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Cites work

• A Bayesian Formulation of Exploratory Data Analysis and Goodness‐of‐fit Testing*
• Exploiting Gene‐Environment Independence for Analysis of Case–Control Studies: An Empirical Bayes‐Type Shrinkage Estimator to Trade‐Off between Bias and Efficiency
• Logistic Bayesian LASSO for identifying association with rare haplotypes and application to age-related macular degeneration
• Logistic disease incidence models and case-control studies
• Retrospective analysis of haplotype-based case-control studies under a flexible model for gene-environment association
• Reversible jump Markov chain Monte Carlo computation and Bayesian model determination

Cited in

(4)

• Logistic Bayesian LASSO for identifying association with rare haplotypes and application to age-related macular degeneration
• A unified method for rare variant analysis of gene-environment interactions
• Detecting rare haplotype association with two correlated phenotypes of binary and continuous types
• Structures and assumptions: strategies to harness gene \(\times\) gene and gene \(\times\) environment interactions in GWAS

Describes a project that uses

Uses Software

• Haploview

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