Dengue disease, basic reproduction number and control

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Publication:2887040

DOI10.1080/00207160.2011.554540zbMATH Open1237.92042DBLPjournals/ijcm/RodriguesMTZ12arXiv1103.1923OpenAlexW2165792753WikidataQ57650881 ScholiaQ57650881MaRDI QIDQ2887040FDOQ2887040


Authors: Helena Sofia Rodrigues, Delfim F. M. Torres, M. Teresa T. Monteiro, A. S. I. Zinober Edit this on Wikidata


Publication date: 15 May 2012

Published in: International Journal of Computer Mathematics (Search for Journal in Brave)

Abstract: Dengue is one of the major international public health concerns. Although progress is underway, developing a vaccine against the disease is challenging. Thus, the main approach to fight the disease is vector control. A model for the transmission of Dengue disease is presented. It consists of eight mutually exclusive compartments representing the human and vector dynamics. It also includes a control parameter (insecticide) in order to fight the mosquito. The model presents three possible equilibria: two disease-free equilibria (DFE) and another endemic equilibrium. It has been proved that a DFE is locally asymptotically stable, whenever a certain epidemiological threshold, known as the basic reproduction number, is less than one. We show that if we apply a minimum level of insecticide, it is possible to maintain the basic reproduction number below unity. A case study, using data of the outbreak that occurred in 2009 in Cape Verde, is presented.


Full work available at URL: https://arxiv.org/abs/1103.1923




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