Bayesian enrichment strategies for randomized discontinuation trials

DOI10.1111/J.1541-0420.2011.01623.XMaRDI QIDQ2894009zbMATH OpenOpenAlexWikidataFDO

Authors Lorenzo Trippa, Gary L. Rosner, P. Müller

Publication date 27 June 2012

Published in Biometrics (Search for Journal in Brave)

Full work available at URL http://europepmc.org/articles/pmc3667626

zbMATH Keywords

clinical trialstumor growth modelsenrichment designsrandomized discontinuation design

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Bayesian problems; characterization of Bayes procedures (62C10)

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Cites work

• A new stochastic Gompertz diffusion process with threshold parameter: computational aspects and applications
• Bayes estimation of reliability for the two-parameter lognormal distribution
• Optimal Design via Curve Fitting of Monte Carlo Experiments
• Optimal Statistical Decisions
• Parameter Estimation in a Gompertzian Stochastic Model for Tumor Growth
• Statistical Methods for Eliciting Probability Distributions
• Stochastic Dominance among Log-Normal Prospects

Cited in

(6)

• Randomized discontinuation trials with binary outcomes
• Optimizing parameters in clinical trials with a randomized start or withdrawal design
• Bayesian designs and the control of frequentist characteristics: a practical solution
• Estimation of Progression-Free Survival for All Treated Patients in the Randomized Discontinuation Trial Design
• Random norming AIDS analysis of non-linear regression models with sequential informative dose selection
• Robust meta‐analytic‐predictive priors in clinical trials with historical control information

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