Optimal therapy protocols in the mathematical model of acute leukemia with several phase constraints
DOI10.1002/OCA.2087zbMATH Open1302.49058OpenAlexW1933519410MaRDI QIDQ2931071FDOQ2931071
Authors: Y. Todorov, F. Nuernberg 
Publication date: 21 November 2014
Published in: Optimal Control Applications \& Methods (Search for Journal in Brave)
Full work available at URL: https://doi.org/10.1002/oca.2087
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Medical applications (general) (92C50) Optimality conditions for problems involving ordinary differential equations (49K15) Applications of optimal control and differential games (49N90)
Cites Work
- A history of the study of solid tumour growth: the contribution of mathematical modelling
- Acute leukemia and chemotherapy: A modeling viewpoint
- Optimal control analysis in the chemotherapy of IgG multiple myeloma
- On strategies on a mathematical model for leukemia therapy
- A mathematical model of neutrophil production and control in normal man
- Combining Gompertzian growth and cell population dynamics
- A Cell Kinetics Justification for Gompertz’ Equation
- Gompertzian growth as a consequence of tumor heterogeneity
- An optimal strategy for leukemia therapy: a multi-objective approach
Cited In (8)
- An optimal strategy for leukemia therapy: a multi-objective approach
- Optimization of combination therapy for chronic myeloid leukemia with dosing constraints
- Optimal control in a mathematical model for leukemia therapy with phase constraints
- On optimal and suboptimal treatment strategies for a mathematical model of leukemia
- Optimal multitherapy strategy in mathematical model of dynamics of the number of nonuniform tumor cells
- Mathematical models of leukaemia and its treatment: a review
- Optimal control of treatment in a mathematical model of chronic myelogenous leukemia
- On strategies on a mathematical model for leukemia therapy
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