A comparison between the diffusion–reaction and slow axonal transport models for predicting tau distribution along an axon

DOI10.1093/IMAMMB/DQU003zbMath1325.92020OpenAlexW2111906815WikidataQ43524216 ScholiaQ43524216MaRDI QIDQ2949685

Andrey V. Kuznetsov, Ivan A. Kuznetsov

Publication date: 2 October 2015

Published in: Mathematical Medicine and Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1093/imammb/dqu003

zbMATH Keywords

analytical solutiondiffusion-reaction modeltau proteinslow axonal transport model

Mathematics Subject Classification ID

Neural biology (92C20) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

Related Items (6)

Bidirectional, unlike unidirectional transport, allows transporting axonal cargos against their concentration gradient ⋮ How the formation of amyloid plaques and neurofibrillary tangles may be related: a mathematical modelling study ⋮ Utilization of the bootstrap method for determining confidence intervals of parameters for a model of MAP1B protein transport in axons ⋮ Modeling tau transport in the axon initial segment ⋮ Simulating tubulin-associated unit transport in an axon: using bootstrapping for estimating confidence intervals of best-fit parameter values obtained from indirect experimental data ⋮ Simulating the effect of formation of amyloid plaques on aggregation of tau protein

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