Simulating the effect of formation of amyloid plaques on aggregation of tau protein
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Publication:5243647
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Cites work
- A comparison between the diffusion-reaction and slow axonal transport models for predicting tau distribution along an axon
- How the formation of amyloid plaques and neurofibrillary tangles may be related: a mathematical modelling study
- On the validity of the steady state assumption of enzyme kinetics
- Optimally weighted \(L^{2}\) distance for functional data
- Simulating tubulin-associated unit transport in an axon: using bootstrapping for estimating confidence intervals of best-fit parameter values obtained from indirect experimental data
Cited in
(13)- Numerical modeling of senile plaque development under conditions of limited diffusivity of amyloid-\(\beta\) monomers
- Modeling the interaction between \(\beta\)-amyloid aggregates and choline acetyltransferase activity and its relation with cholinergic dysfunction through two-enzyme/two-compartment model
- The growth rate of senile plaques is determined by the competition between the rate of deposition of free A\(\beta\) aggregates into plaques and the autocatalytic production of free A\(\beta\) aggregates
- What can trigger the onset of Parkinson's disease -- A modeling study based on a compartmental model of -synuclein transport and aggregation in neurons
- Towards optimal control of amyloid fibrillation
- A continuous-time mathematical model and discrete approximations for the aggregation of \(\beta \)-amyloid
- Bidirectional, unlike unidirectional transport, allows transporting axonal cargos against their concentration gradient
- Modeling tau transport in the axon initial segment
- A mathematical model for amyloid- aggregation in the presence of metal ions: a timescale analysis for the progress of Alzheimer disease
- Modeling neurodegeneration in chronic traumatic encephalopathy using gradient damage models
- Astrocytic clearance and fragmentation of toxic proteins in Alzheimer's disease on large-scale brain networks
- A mathematical model demonstrating the role of interstitial fluid flow on the clearance and accumulation of amyloid \(\beta\) in the brain
- How the formation of amyloid plaques and neurofibrillary tangles may be related: a mathematical modelling study
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