AGGrEGATOr: A Gene-based GEne-Gene interActTiOn test for case-control association studies

DOI10.1515/SAGMB-2015-0074zbMATH Open1343.92010OpenAlexW2331005908WikidataQ39970243 ScholiaQ39970243MaRDI QIDQ306685FDOQ306685

Authors: Mathieu Emily 

Publication date: 1 September 2016

Published in: Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1515/sagmb-2015-0074

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zbMATH Keywords

gene-gene interactiongenome-wide associationminP

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) General biostatistics (92B15) Genetics and epigenetics (92D10)

Cites Work

• Computation of multivariate normal and \(t\) probabilities
• An entropy-based approach for testing genetic epistasis underlying complex diseases
• A powerful truncated tail strength method for testing multiple null hypotheses in one dataset

Cited In (2)

• Testing for gene-gene interaction in case-control GWAS
• Omnibus testing approach for gene-based gene-gene interaction

Uses Software

• R
• IMPUTE
• HapSim

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