Estimation of spontaneous mutation rates

DOI10.1111/1541-0420.00065MaRDI QIDQ3079151zbMATH OpenOpenAlexWikidataFDO

Authors Loki Natarajan, Charles C. Berry, Christoph Gasche

Publication date 1 March 2011

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1111/1541-0420.00065

zbMATH Keywords

cancerstochastic processesmutation rateLuria-Delbrück distribution

Mathematics Subject Classification ID

Estimation in survival analysis and censored data (62N02) Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Genetics and epigenetics (92D10)

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Cites work

• scientific article; zbMATH DE number 3115405 (Why is no real title available?)
• scientific article; zbMATH DE number 3073509 (Why is no real title available?)
• Analysis of the Luria–Delbrück distribution using discrete convolution powers
• Progress of a half century in the study of the Luria-Delbrück distribution

Cited in

(15)

• A computational model for radiation-induced cellular transformation to in vitro irradiation of cells by acute doses of X-rays
• Mean field mutation dynamics and the continuous Luria-Delbrück distribution
• Approximations for Expected Generation Number
• A stochastic model for estimation of mutation rates in multiple-replication proliferation processes
• Inverse problem approaches for mutation laws in heterogeneous tumours with local and nonlocal dynamics
• A generalized Luria-Delbrück model
• The Luria-Delbrück experiment: are mutations spontaneous or directed?
• Somatic mosaicism and cancer: inference based on a conditional Luria-Delbrück distribution
• On Haldane's formulation of Luria and Delbrück's mutation model
• On an unbiased and consistent estimator for mutation rates
• Are mutations spontaneous or directed?
• Survival analysis of DNA mutation motifs with penalized proportional hazards
• Estimating the scaled mutation rate and mutation bias with site frequency data
• Bivariate Poisson models with varying offsets: an application to the paired mitochondrial DNA dataset
• A disequilibrium model for detecting genetic mutations for cancer

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