Benefit–Risk Evaluation of Multi-Stage Adaptive Designs

DOI10.1081/SQA-200027049zbMath1054.62084OpenAlexW2017008232MaRDI QIDQ3155694

Gordon Pledger, Qing Liu, Keaven M. Anderson

Publication date: 18 January 2005

Published in: Sequential Analysis (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1081/sqa-200027049

zbMATH Keywords

clinical trialstype I error ratesample size adjustmentconditional error

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05)

Cites Work

• On Sample Size and Inference for Two‐Stage Adaptive Designs
• Adaptive Group Sequential Designs for Clinical Trials: Combining the Advantages of Adaptive and of Classical Group Sequential Approaches
• Self-Designing Two-Stage Trials to Minimize Expected Costs
• Discrete Sequential Boundaries for Clinical Trials
• Two-stage selection and testing designs for comparative clinical trials
• Designed Extension of Studies Based on Conditional Power
• On the inefficiency of the adaptive design for monitoring clinical trials
• A Unified Theory of Two-Stage Adaptive Designs
• Nonparametric Estimation of a Delay Distribution Based on Left‐Censored and Right‐Truncated Data
• An Improved Double Sampling Procedure Based on the Variance
• A Two-Sample Test for a Linear Hypothesis Whose Power is Independent of the Variance