Response-adaptive designs for clinical trials: simultaneous learning from multiple patients

DOI10.1016/J.EJOR.2015.06.077zbMATH Open1346.90528OpenAlexW3121380969MaRDI QIDQ320737FDOQ320737

John R. Birge, Vishal Ahuja

Publication date: 7 October 2016

Published in: European Journal of Operational Research (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.ejor.2015.06.077

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zbMATH Keywords

OR in health servicesMarkov decision processBayesian learningadaptive clinical trialsstents

Mathematics Subject Classification ID

Bayesian inference (62F15) Applications of statistics to biology and medical sciences; meta analysis (62P10) Case-oriented studies in operations research (90B90) Markov and semi-Markov decision processes (90C40)

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Cited In (6)

• Clinical site selection problems with probabilistic constraints
• Dynamic Programming for Response-Adaptive Dose-Finding Clinical Trials
• An Approximation Approach for Response-Adaptive Clinical Trial Design
• Bayesian learning of dose-response parameters from a cohort under response-guided dosing
• Intermediate Monitoring, Sample Size Reassessment, and Multi-Treatment Optimal Response-Adaptive Designs for Phase III Clinical Trials with More Than One Constraint
• Dynamic Programs with Shared Resources and Signals: Dynamic Fluid Policies and Asymptotic Optimality

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