Design and Analysis of Group Sequential Clinical Trials with Multiple Primary Endpoints

DOI10.1111/J.0006-341X.2004.00146.XMaRDI QIDQ3435673zbMATHWikidataFDO

Authors Michael R. Kosorok, Yuanjun Shi, David L. Demets

Publication date 7 May 2007

Published in Biometrics (Search for Journal in Brave)

zbMATH Keywords

time-to-event datasample sizemultivariate outcomesalpha-spending functionbeta-spending function

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05)

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Cites work

• scientific article; zbMATH DE number 3984308 (Why is no real title available?)
• scientific article; zbMATH DE number 49697 (Why is no real title available?)
• Group sequential designs for one-sided and two-sided hypothesis testing with provision for early stopping in favor of the null hypothesis
• Repeated Significance Testing for a General Class of Statistics Used in Censored Survival Analysis

Cited in

(17)

• The simultaneous analysis of mixed discrete and continuous outcomes using nonlinear threshold models
• Statistical monitoring of clinical trials with multivariate response and/or multiple arms: a flexible approach
• Exact sequential analysis for multiple weighted binomial end points
• Multistage nonparametric tests for treatment comparisons in clinical trials with multiple primary endpoints
• Non-parametric group sequential designs in randomized clinical trials
• Interim evaluation of efficacy or futility in group‐sequential trials with multiple co‐primary endpoints
• Simultaneous population enrichment and endpoint selection in phase 3 randomized controlled trials: An adaptive group sequential design with two binary alternative primary endpoints
• Group-Sequential Clinical Trials with Multiple Co-Objectives
• A Geometric Approach to Comparing Treatments for Rapidly Fatal Diseases
• Evaluating co-primary endpoints collectively in clinical trials
• A Bayesian Group Sequential Approach for Multiple Endpoints
• Testing a Primary and a Secondary Endpoint in a Group Sequential Design
• A nonparametric test for the evaluation of group sequential clinical trials with covariate information
• Longitudinal clinical trials with adaptive choice of follow-up time
• BAGS: a Bayesian adaptive group sequential trial design with subgroup-specific survival comparisons
• Closed Testing Procedures for Group Sequential Clinical Trials with Multiple Endpoints
• Group-sequential logrank methods for trial designs using bivariate non-competing event-time outcomes

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