Practical Design Strategies for the Detection of Drug Synergy

DOI10.1016/S1571-0653(04)00558-XMaRDI QIDQ3439062zbMATHFDO

Authors Timothy E. O'Brien

Publication date 29 May 2007

Published in Electronic Notes in Discrete Mathematics (Search for Journal in Brave)

Mathematics Subject Classification ID

General nonlinear regression (62J02) Optimal statistical designs (62K05)

Recommendations

• Simple Designs and Model-Free Tests for Synergy
• Maximin designs for the detection of synergistic effects
• Optimum mixture design for the detection of synergistic effects
• Compromise design for combination experiment of two drugs
• Optimal 3×3 factorial and 3-ray designs for drug interaction experiments with dichotomous responses

Cites work

• scientific article; zbMATH DE number 802801 (Why is no real title available?)
• scientific article; zbMATH DE number 3073468 (Why is no real title available?)
• Design of Experiments for Subsets of Parameters
• Optimal Bayesian design applied to logistic regression experiments
• Optimal design: Variation in structure and performance under change of criterion

Cited in

(3)

• Asynergistic Regression Based on Maximized Rank Correlation
• Multi-drug combination designs with experiments in silico
• Detection of synergistic combinatorial perturbations by a bifurcation-based approach

This page was built for publication: Practical Design Strategies for the Detection of Drug Synergy

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q3439062)