Optimal 3×3 factorial and 3-ray designs for drug interaction experiments with dichotomous responses

DOI10.1080/03610928908830065MaRDI QIDQ3474103zbMATH OpenOpenAlexFDO

Authors Marshall N. Brunden, Thomas J. Vidmar

Publication date 1989

Published in Communications in Statistics: Theory and Methods (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1080/03610928908830065

zbMATH Keywords

D-optimalitydesigndrug combinationefficiencylogistic modelsimple similar action

Mathematics Subject Classification ID

Optimal statistical designs (62K05) Factorial statistical designs (62K15) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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(5)

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• A-optimal completely randomized designs for incomplete factorial structures with three factors
• Empirical evaluation of sufficient similarity in dose-response for environmental risk assessment of chemical mixtures
• Practical Design Strategies for the Detection of Drug Synergy
• Blends of statistical designs for dose-response studies¹

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