Optimal 3×3 factorial and 3-ray designs for drug interaction experiments with dichotomous responses

DOI10.1080/03610928908830065zbMATH Open0696.62313OpenAlexW2067800584MaRDI QIDQ3474103FDOQ3474103

Authors: Marshall N. Brunden, Thomas J. Vidmar 

Publication date: 1989

Published in: Communications in Statistics: Theory and Methods (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/03610928908830065

Recommendations

• \(D\)-optimal designs for the two-variable binary logistic regression model with interaction
• Optimum experimental designs for comparative bioavailability studies
• Optimal experimental designs for estimating the drug combination index in toxicology
• Experimental designs for drug combination studies
• scientific article; zbMATH DE number 4064300

zbMATH Keywords

D-optimalityefficiencydesignlogistic modeldrug combinationsimple similar action

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05) Factorial statistical designs (62K15)

Cited In (4)

• Practical Design Strategies for the Detection of Drug Synergy
• Experimental designs for drug combination studies
• Empirical evaluation of sufficient similarity in dose-response for environmental risk assessment of chemical mixtures
• A-optimal completely randomized designs for incomplete factorial structures with three factors

This page was built for publication: Optimal 3×3 factorial and 3-ray designs for drug interaction experiments with dichotomous responses

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q3474103)