A two-sample parametric group sequential procedure for monitoring clinical trials

DOI10.1080/03610929008830367MaRDI QIDQ3978089zbMATH OpenOpenAlexFDO

Authors D. J. Richardson

Publication date 25 June 1992

Published in Communications in Statistics: Theory and Methods (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1080/03610929008830367

zbMATH Keywords

clinical trialsmartingaleBrownian motion processlogrank statisticgroup sequential proceduretwo-sample procedure

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05)

Recommendations

• Group sequential analysis op a clinical trial with repeated measurements
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• Flexibly Monitoring Group Sequential Survival Trials When Testing is Based Upon a Weighted Log-Rank Statistic

Cites work

• scientific article; zbMATH DE number 3274494 (Why is no real title available?)
• Central limit theorems for local martingales
• Design and analysis of group sequential tests based on the type I error spending rate function
• Discrete Sequential Boundaries for Clinical Trials
• Nonparametric inference for a family of counting processes
• On large sample sequential analysis with applications to survivorship data
• Repeated Significance Testing for a General Class of Statistics Used in Censored Survival Analysis
• Two-Sample Repeated Significance Tests Based on the Modified Wilcoxon Statistic
• Understanding Cox's Regression Model: A Martingale Approach

Cited in

(3)

• Study Duration for Clinical Trials with Survival Response and Early Stopping Rule
• Some extensions of Langenberg model for clinical trials with delayed observations normally distributed responses
• Exact Permutational Tests for Group Sequential Clinical Trials

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Uses Software

• AS 183

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