Mathematical modelling and computational study of two-dimensional and three-dimensional dynamics of receptor-ligand interactions in signalling response mechanisms

DOI10.1007/s00285-013-0712-4zbMath1302.92041OpenAlexW1974215082WikidataQ45191889 ScholiaQ45191889MaRDI QIDQ404786

Juan J. Gálvez, Jesús Gálvez, Pilar García-Peñarrubia

Publication date: 4 September 2014

Published in: Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/s00285-013-0712-4

zbMATH Keywords

reduction of dimensionality2D and 3D receptor-ligand bindingsignalling response mechanisms

Mathematics Subject Classification ID

Computational methods for problems pertaining to biology (92-08) Software, source code, etc. for problems pertaining to biology (92-04) Systems biology, networks (92C42)

Related Items

Global well-posedness for volume–surface reaction–diffusion systems ⋮ Coupled Bulk-Surface Free Boundary Problems Arising from a Mathematical Model of Receptor-Ligand Dynamics ⋮ Multiscale Analysis and Simulation of a Signaling Process With Surface Diffusion ⋮ A Coupled Ligand-Receptor Bulk-Surface System on a Moving Domain: Well Posedness, Regularity, and Convergence to Equilibrium

Cites Work

• Model of cell signal transduction in a three-dimensional domain
• Spatio-temporal modelling of the NF-\(\kappa\)B intracellular signalling pathway: the roles of diffusion, active transport, and cell geometry
• Dynamics and stability of a three-dimensional model of cell signal transduction