Comparison of Methods for Estimating the Number of True Null Hypotheses in Multiplicity Testing

DOI10.1081/BIP-120024202MaRDI QIDQ4430342zbMATH OpenOpenAlexWikidataFDO

Authors Huey-Miin Hsueh, James J. Chen, Ralph L. Kodell

Publication date 7 October 2003

Published in Journal of Biopharmaceutical Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1081/bip-120024202

Mathematics Subject Classification ID

Paired and multiple comparisons; multiple testing (62J15) Applications of statistics to biology and medical sciences; meta analysis (62P10) Monte Carlo methods (65C05)

Recommendations

• Comparisons of estimators of the number of true null hypotheses and adaptive FDR procedures in multiplicity testing
• Estimating the number of true null hypotheses in multiple hypothesis testing
• A clarifying comparison of methods for controlling the false discovery rate
• On estimating the proportion of true null hypotheses for false discovery rate controlling procedures in exploratory DNA microarray studies
• Estimation of False Discovery Rates in Multiple Testing: Application to Gene Microarray Data

Cites work

• A Direct Approach to False Discovery Rates
• A modified Benjamini-Hochberg multiple comparisons procedure for controlling the false discovery rate
• Familywise Robustness Criteria for Multiple-Comparison Procedures
• Significance analysis of microarrays applied to the ionizing radiation response

Cited in

(21)

• Estimating the proportion of false null hypotheses among a large number of independently tested hypotheses
• Estimating the proportion of true null hypotheses in multiple testing problems
• An evaluation of statistical methods for aggregate patterns of replication failure
• A powerful truncated tail strength method for testing multiple null hypotheses in one dataset
• Supporting informationa robust method for large-scale multiple hypotheses testing
• Comparisons of estimators of the number of true null hypotheses and adaptive FDR procedures in multiplicity testing
• Estimation of False Discovery Rates in Multiple Testing: Application to Gene Microarray Data
• Multiple-Testing Strategy for Analyzing cDNA Array Data on Gene Expression
• Efficient estimation of the number of false positives in high-throughput screening
• A look at multiplicity through misclassification
• Estimating the number of equal components for two high-dimensional mean vectors
• Two new estimators for the proportion of true null hypotheses in multiple test
• Estimating the proportion of true null hypotheses using the pattern of observed \(p\)-values
• Incorporating the number of true null hypotheses to improve power in multiple testing: application to gene microarray data
• Sample Size Calculations Based on Ranking and Selection in Microarray Experiments
• Exploring the Information in p‐Values for the Analysis and Planning of Multiple‐Test Experiments
• A Statistical Framework for Hypothesis Testing in Real Data Comparison Studies
• An improved permutation-based FDR estimator for heavy-tailed data
• False discovery rate envelopes
• Estimating the number of true null hypotheses in multiple hypothesis testing
• The beta-binomial distribution for estimating the number of false rejections in microarray gene expression studies

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