Statistical Analysis of Ion Channel Data Using Hidden Markov Models With Correlated State-Dependent Noise and Filtering

DOI10.1198/016214501753208519MaRDI QIDQ4468282zbMATH OpenOpenAlexFDO

Authors J. G. Schouten, Mathisca de Gunst, H. R. Künsch

Publication date 10 June 2004

Published in Journal of the American Statistical Association (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1198/016214501753208519

zbMATH Keywords

Kalman filterGibbs samplersignal reconstruction

Mathematics Subject Classification ID

Point estimation (62F10) Bayesian inference (62F15) Nonparametric estimation (62G05) Applications of statistics to biology and medical sciences; meta analysis (62P10) Numerical analysis or methods applied to Markov chains (65C40) Cell biology (92C37)

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• MCMC for hidden Markov models incorporating aggregation of states and filtering
• Evaluation and Estimation of Various Markov Models with Applications to Membrane Channel Kinetics
• Extracting state transition dynamics from multiple spike trains using hidden Markov models with correlated Poisson distribution
• Noise analysis of an ion channel in the cardiac myocyte-study based on a Markov model
• Model selection and parameter estimation for ion channel recordings with an application to the \(K^{+}\) outward-rectifier in barley leaf
• Efficient methods for sampling spike trains in networks of coupled neurons
• Hidden Markov analysis of mechanosensitive ion channel gating
• Model selection for hidden Markov models of ion channel data by reversible jump Markov chain Monte Carlo
• Asymptotic behavior of Bayes estimators for hidden Markov models with application to ion channels
• Robust inference and modelling for the single ion channel
• Identifying the generator matrix of a stationary Markov chain using partially observable data

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