Alternative to Ritt's pseudodivision for finding the input-output equations of multi-output models

DOI10.1016/J.MBS.2012.04.008zbMATH Open1320.93035arXiv1203.4485OpenAlexW2009094692WikidataQ51364080 ScholiaQ51364080MaRDI QIDQ453072FDOQ453072

Chris Anderson, Joseph J. III DiStefano, Nicolette Meshkat

Publication date: 18 September 2012

Published in: Mathematical Biosciences (Search for Journal in Brave)

Abstract: Differential algebra approaches to structural identifiability analysis of a dynamic system model in many instances heavily depend upon Ritt's pseudodivision at an early step in analysis. The pseudodivision algorithm is used to find the characteristic set, of which a subset, the input-output equations, is used for identifiability analysis. A simpler algorithm is proposed for this step, using Gr"obner Bases, along with a proof of the method that includes a reduced upper bound on derivative requirements. Efficacy of the new algorithm is illustrated with two biosystem model examples.

Full work available at URL: https://arxiv.org/abs/1203.4485

zbMATH Keywords

identifiability[https://portal.mardi4nfdi.de/w/index.php?title=+Special%3ASearch&search=Gr%EF%BF%BD%EF%BF%BDbner+basis&go=Go Gr��bner basis]differential algebraRitt's pseudodivision

Mathematics Subject Classification ID

Inverse problems involving ordinary differential equations (34A55) System identification (93B30)

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Cited In (9)

• Variable structure control of a singular predator-prey system with the influence of toxic substances
• A parameter-free model comparison test using differential algebra
• A confidence building exercise in data and identifiability: modeling cancer chemotherapy as a case study
• A minimal model of T cell avidity may identify subtherapeutic vaccine schedules
• Identifiable reparametrizations of linear compartment models
• Sensitivity analysis and practical identifiability of some mathematical models in biology
• Computing human to human avian influenza \(\mathcal{R}_0\) via transmission chains and parameter estimation
• Identifiability results for several classes of linear compartment models
• A systematic approach for doing an a priori identifiability study of dynamical nonlinear models

Uses Software

• DAISY
• diffgrob2

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