Adjoint eigenfunctions of temporally recurrent single-spiral solutions in a simple model of atrial fibrillation

DOI10.1063/1.4962644MaRDI QIDQ4606920zbMATH OpenOpenAlexWikidataFDO

Authors Christopher D. Marcotte, Roman O. Grigoriev

Publication date 9 March 2018

Published in Chaos: An Interdisciplinary Journal of Nonlinear Science (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1605.00115

Mathematics Subject Classification ID

Physiology (general) (92C30) Spectral theory and eigenvalue problems for partial differential equations (35P99)

Abstract: This paper introduces a numerical method for computing the spectrum of adjoint (left) eigenfunctions of spiral wave solutions to reaction-diffusion systems in arbitrary geometries. The method is illustrated by computing over a hundred eigenfunctions associated with an unstable time-periodic single-spiral solution of the Karma model on a square domain. We show that all leading adjoint eigenfunctions are exponentially localized in the vicinity of the spiral tip, although the marginal modes (response functions) demonstrate the strongest localization. We also discuss the implications of the localization for the dynamics and control of unstable spiral waves. In particular, the interaction with no-flux boundaries leads to a drift of spiral waves which can be understood with the help of the response functions.

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Cited in

(5)

• Dynamical mechanism of atrial fibrillation: a topological approach
• Behavior of spiral wave spectra with a rank-deficient diffusion matrix
• Spiral Waves: Linear and Nonlinear Theory
• Computation of Spiral Spectra
• Determining the source of period-doubling instabilities in spiral waves

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