Lévy noise induced transition and enhanced stability in a gene regulatory network
From MaRDI portal
Abstract: Important effects of noise on a one-dimensional gene expression model involving a single gene have recently been discussed. However, few works have been devoted to the transition in two-dimensional models which include the interaction of genes. Therefore, we investigate here, a quantitative two-dimensional model (MeKS network) of gene expression dynamics describing the competence development in the B. subtilis under the influence of L'evy as well as Brownian motions, where noises can do the B. subtilis a favor in nutrient depletion. To analyze the transitions between the vegetative and the competence regions therein, two deterministic quantities, the mean first exit time (MFET) and the first escape probability (FEP) from a microscopic perspective, as well as their averaged versions from a macroscopic perspective, are applied. The relative contribution factor (RCF), the ratio of non-Gaussian and Gaussian noise strengths, is adopted to implement optimal control in these transitions. Schematic representations indicate that there exists an optimum choice that makes the transition occurring at the highest probability. Additionally, we use a geometric concept, the stochastic basin of attraction, to exhibit a pictorial comprehension about the influence of the L'{e}vy motion on the basin stability of the competence state.
Recommendations
- Most probable dynamics of a genetic regulatory network under stable Lévy noise
- Noises-induced toggle switch and stability in a gene regulation network
- Nonlocal dynamics in a gene regulatory system with tempered stable Lévy noise
- Stability of a gene transcriptional regulatory system under non-Gaussian noise
- Delay and noise induced regime shift and enhanced stability in gene expression dynamics
- Data-driven approximation for extracting the transition dynamics of a genetic regulatory network with non-Gaussian Lévy noise
Cites work
- A computational analysis for mean exit time under non-Gaussian Lévy noises
- A note on compact finite difference method for reaction-diffusion equations with delay
- A two-level linearized compact ADI scheme for two-dimensional nonlinear reaction-diffusion equations
- An introduction to stochastic dynamics
- Asymmetric non-Gaussian effects in a tumor growth model with immunization
- Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible
- Data assimilation and parameter estimation for a multiscale stochastic system with \(\alpha \)-stable Lévy noise
- Delay and noise induced regime shift and enhanced stability in gene expression dynamics
- Dynamical behavior of the activator-repressor circuit model under random fluctuations
- First exit times for Lévy-driven diffusions with exponentially light jumps
- Governing equations for probability densities of Marcus stochastic differential equations with Lévy noise
- scientific article; zbMATH DE number 614990 (Why is no real title available?)
- scientific article; zbMATH DE number 1402217 (Why is no real title available?)
- LÉVY FLIGHT SUPERDIFFUSION: AN INTRODUCTION
- Lévy flights in evolutionary ecology
- Lévy flights: transitions and meta-stability
- Lévy noise-induced escape in an excitable system
- Lévy Processes and Stochastic Calculus
- Mean exit time and escape probability for dynamical systems driven by Lévy noises
- Noise- and delay-induced regime shifts in an ecological system of vegetation
- Numerical methods for the mean exit time and escape probability of two-dimensional stochastic dynamical systems with non-Gaussian noises
- Split Newton iterative algorithm and its application
- Stochastic basins of attraction for metastable states
- Stochastic methods. A handbook for the natural and social sciences
- Stochastic processes in cell biology
- Stochastic processes in physics and chemistry.
Cited in
(25)- Most probable dynamics of a genetic regulatory network under stable Lévy noise
- Extracting governing laws from sample path data of non-Gaussian stochastic dynamical systems
- A data-driven approach for discovering stochastic dynamical systems with non-Gaussian Lévy noise
- Oscillation dynamics of MeKS core module containing positive and negative feedback loops with time delay
- Nonlocal dynamics in a gene regulatory system with tempered stable Lévy noise
- Quasi-threshold phenomenon in noise-driven Higgins model
- Statistical characteristics of the first passage time analysis for the gene regulatory circuit in \textit{Bacillus subtilis} by cell mapping method
- Nonlocal dynamics for non-Gaussian systems arising in biophysical modeling
- Effects of Lévy noise on the Fitzhugh-Nagumo model: a perspective on the maximal likely trajectories
- Stochastic resonance in a genetic toggle model with harmonic excitation and Lévy noise
- Likelihood for transcriptions in a genetic regulatory system under asymmetric stable Lévy noise
- Most probable dynamics of stochastic dynamical systems with exponentially light jump fluctuations
- Dynamical transition of phenotypic states in breast cancer system with Lévy noise
- Cross-correlated sine-Wiener noises-induced transitions in a tumor growth system
- State transitions in the Morris-Lecar model under stable Lévy noise
- A stochastic differential equation driven by Poisson random measure and its application in a duopoly market
- State estimation results for genetic regulatory networks with Lévy-type noise
- Data-driven discovery of stochastic dynamical systems with \(\alpha\)-stable Lévy noise based on residual networks
- An Onsager-Machlup approach to the most probable transition pathway for a genetic regulatory network
- The most probable transition pathway of a predator-prey system under noise
- Stochastic dynamical behaviors of SOS/ERK signaling pathway perturbated by external noise
- Multi-scaling reservoir computing learns noise-induced transitions with Lévy noise
- Transition path theory for Lévy-type processes: SDE representation and statistics
- Transition and basin stability in a delayed Fitzhugh-Nagumo neural model under non-Gaussian colored noise
- Early warning of noise-induced critical transitions in two-dimensional ecosystems
This page was built for publication: Lévy noise induced transition and enhanced stability in a gene regulatory network
Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q4683680)
