p-value calibration for multiple testing problems in genomics

DOI10.1515/SAGMB-2013-0074MaRDI QIDQ482816zbMATH OpenOpenAlexWikidataFDO

Authors John P. Ferguson, Dean Palejev

Publication date 6 January 2015

Published in Statistical Applications in Genetics and Molecular Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1515/sagmb-2013-0074

zbMATH Keywords

\(p\)-valuecalibrationconditional likelihoodconservative testFDR correction

Mathematics Subject Classification ID

General biostatistics (92B15) Biochemistry, molecular biology (92C40)

Recommendations

• Resampling-based multiple testing for microarray data analysis (With comments)
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• Statistical significance for genomewide studies
• Shrunken p‐Values for Assessing Differential Expression with Applications to Genomic Data Analysis
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Cites work

• All of Nonparametric Statistics
• Calibration of values for testing precise null hypotheses
• Detecting mutations in mixed sample sequencing data using empirical Bayes
• Genomic Control for Association Studies
• scientific article; zbMATH DE number 720689 (Why is no real title available?)
• Microarrays, empirical Bayes and the two-groups model
• Testing Statistical Hypotheses

Cited in

(2)

• D\_CDF test of negative \(\log\) transformed \(p\)-values with application to genetic pathway analysis
• Accurate and flexible power calculations on the spot: applications to genomic research

Describes a project that uses

Uses Software

• DEseq
• Eigenstrat
• R
• recount

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