Optimal control of a heroin epidemic mathematical model

DOI10.1080/02331934.2021.2009823zbMATH Open1506.34068arXiv2111.05906OpenAlexW4206810087MaRDI QIDQ5044094FDOQ5044094

Delfim F. M. Torres, Amar Debbouche, Puthur Thangaraj Sowndarrajan, L. Shangerganesh

Publication date: 24 October 2022

Published in: Optimization (Search for Journal in Brave)

Abstract: A heroin epidemic mathematical model with prevention information and treatment, as control interventions, is analyzed, assuming that an individual's behavioral response depends on the spreading of information about the effects of heroin. Such information creates awareness, which helps individuals to participate in preventive education and self-protective schemes with additional efforts. We prove that the basic reproduction number is the threshold of local stability of a drug-free and endemic equilibrium. Then, we formulate an optimal control problem to minimize the total number of drug users and the cost associated with prevention education measures and treatment. We prove existence of an optimal control and derive its characterization through Pontryagin's maximum principle. The resulting optimality system is solved numerically. We observe that among all possible strategies, the most effective and cost-less is to implement both control policies.

Full work available at URL: https://arxiv.org/abs/2111.05906

zbMATH Keywords

optimal controlstability analysisbehavioural changeheroin epidemic mathematical model

Mathematics Subject Classification ID

Epidemiology (92D30) Qualitative investigation and simulation of ordinary differential equation models (34C60) Topological structure of integral curves, singular points, limit cycles of ordinary differential equations (34C05) Asymptotic properties of solutions to ordinary differential equations (34D05) Stability of solutions to ordinary differential equations (34D20) Global stability of solutions to ordinary differential equations (34D23) Existence theories for optimal control problems involving ordinary differential equations (49J15)

Cites Work

• Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission
• A note on heroin epidemics
• A note on global stability for a heroin epidemic model with distributed delay
• Dynamic behaviour for a nonautonomous heroin epidemic model with time delay
• Optimal control for a tuberculosis model with reinfection and post-exposure interventions
• Heroin epidemics, treatment and ODE modelling
• Keeping Options Open: an Optimal Control Model with Trajectories That Reach a DNSS Point in Positive Time
• Title not available (Why is that?)
• Title not available (Why is that?)
• Global behaviour of a heroin epidemic model with distributed delays
• Title not available (Why is that?)
• Title not available (Why is that?)
• Title not available (Why is that?)
• Modeling illicit drug use dynamics and its optimal control analysis
• Vaccination and treatment as control interventions in an infectious disease model with their cost optimization
• Ebola model and optimal control with vaccination constraints
• Analysis of a heroin epidemic model with saturated treatment function
• Multiobjective optimization to a TB-HIV/AIDS coinfection optimal control problem
• Modelling and optimal control of HIV/AIDS prevention through PrEP and limited treatment
• Pest control using farming awareness: impact of time delays and optimal use of biopesticides
• The impact of self-protective measures in the optimal interventions for controlling infectious diseases of human population
• Modeling the prescription opioid epidemic
• A stochastic time-delayed model for the effectiveness of Moroccan COVID-19 deconfinement strategy
• Analysis of an age-structured multi-group heroin epidemic model
• Optimal control strategies for a heroin epidemic model with age-dependent susceptibility and recovery-age
• Correction to: ``Optimal control strategies for a heroin epidemic model with age-dependent susceptibility and recovery-age
• Use of optimal control models to predict treatment time for managing tick-borne disease

Cited In (4)

• Optimal Control of Drug Epidemics: Prevent and Treat—But Not at the Same Time?
• Title not available (Why is that?)
• Mathematical modeling and optimal control strategy for a discrete time drug consumption model
• Dynamic analysis of a drug transmission model with anti-drug education and media coverage

This page was built for publication: Optimal control of a heroin epidemic mathematical model

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q5044094)