Distribution theory following blinded and unblinded sample size re-estimation under parametric models

DOI10.1080/03610918.2019.1692030OpenAlexW2990098362MaRDI QIDQ5082954

Sergey Tarima, Nancy Flournoy

Publication date: 21 June 2022

Published in: Communications in Statistics - Simulation and Computation (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1080/03610918.2019.1692030

zbMATH Keywords

maximum likelihood estimationlocal alternativesadaptive designasymptotic distribution theoryblinded data

Mathematics Subject Classification ID

Statistics (62-XX)

Related Items

Posterior alternatives with informative early stopping ⋮ Efficiency of observed information adaptive designs in linear models

Cites Work

• Unnamed Item
• Two-stage adaptive optimal design with fixed first-stage sample size
• Asymptotics in response-adaptive designs generated by a two-color, randomly reinforced urn
• Nonparametric estimators of probability characteristics using unbiased prior conditions
• Asymptotic properties of maximum likelihood estimators with sample size recalculation
• Sample size re-estimation without unblinding for normally distributed outcomes with unknown variance
• Asymptotic Statistics
• Modification of Sample Size in Group Sequential Clinical Trials
• Probabilistic Foundation of Confirmatory Adaptive Designs
• Sample Size Calculation and Blinded Sample Size Recalculation in Clinical Trials Where the Treatment Effect is Measured by the Relative Risk
• A sample size adjustment procedure for clinical trials based on conditional power
• Conditional Estimation in Two-Stage Adaptive Designs