The Status of the QSSA Approximation in Stochastic Simulations of Reaction Networks

DOI10.1007/978-3-030-38230-8_10zbMath1448.92094OpenAlexW3015534445MaRDI QIDQ5118790

Ana Victoria Ponce Bobadilla, Bartosz J. Bartmanski, Ramon Grima, Hans G. Othmer

Publication date: 27 August 2020

Published in: 2018 MATRIX Annals (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1007/978-3-030-38230-8_10

zbMATH Keywords

stochastic simulationsMichaelis-Menten kineticsreaction networksquasi steady-state approximation

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Applications of stochastic analysis (to PDEs, etc.) (60H30)

Related Items (2)

On the quasi-steady-state approximation in an open Michaelis-Menten reaction mechanism ⋮ On the validity of the stochastic quasi-steady-state approximation in open enzyme catalyzed reactions: timescale separation or singular perturbation?

Cites Work

• Unnamed Item
• A multi-time-scale analysis of chemical reaction networks. II: Stochastic systems
• Separation of time-scales and model reduction for stochastic reaction networks
• A multi-time-scale analysis of chemical reaction networks. I: Deterministic systems
• The Quasi-Steady-State Assumption: A Case Study in Perturbation

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