A statistical model to assess (allele-specific) associations between gene expression and epigenetic features using sequencing data

DOI10.1214/16-AOAS973zbMATH Open1454.62384OpenAlexW2571531605WikidataQ42374668 ScholiaQ42374668MaRDI QIDQ512430FDOQ512430

Authors: Naim U. Rashid, Wei Sun, Joseph G. Ibrahim 

Publication date: 24 February 2017

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1214/16-aoas973

Recommendations

• Wavelet-based genetic association analysis of functional phenotypes arising from high-throughput sequencing assays
• Fully Bayesian analysis of allele-specific RNA-seq data
• Improved detection of epigenomic marks with mixed-effects hidden Markov models
• Estimating DNA methylation levels by joint modeling of multiple methylation profiles from microarray data
• Contrastive latent variable modeling with application to case-control sequencing experiments

zbMATH Keywords

geneticsRNA-seqgenomicsbivariate binomial logistic-normal (BBLN) distributionbivariate Poisson log-normal (BPLN) distributionDNase-seq

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Protein sequences, DNA sequences (92D20)

Cited In (2)

• Wavelet-based genetic association analysis of functional phenotypes arising from high-throughput sequencing assays
• A random coefficients model for regional co-expression associated with DNA copy number

This page was built for publication: A statistical model to assess (allele-specific) associations between gene expression and epigenetic features using sequencing data

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q512430)