A network epidemic model with preventive rewiring: comparative analysis of the initial phase

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Abstract: This paper is concerned with stochastic SIR and SEIR epidemic models on random networks in which individuals may rewire away from infected neighbors at some rate omega (and reconnect to non-infectious individuals with probability alpha or else simply drop the edge if alpha=0), so-called preventive rewiring. The models are denoted SIR-omega and SEIR-omega, and we focus attention on the early stages of an outbreak, where we derive expression for the basic reproduction number R0 and the expected degree of the infectious nodes E(DI) using two different approximation approaches. The first approach approximates the early spread of an epidemic by a branching process, whereas the second one uses pair approximation. The expressions are compared with the corresponding empirical means obtained from stochastic simulations of SIR-omega and SEIR-omega epidemics on Poisson and scale-free networks. Without rewiring of exposed nodes, the two approaches predict the same epidemic threshold and the same E(DI) for both types of epidemics, the latter being very close to the mean degree obtained from simulated epidemics over Poisson networks. Above the epidemic threshold, pairwise models overestimate the value of R0 computed from simulations, which turns out to be very close to the one predicted by the branching process approximation. When exposed individuals also rewire with alpha>0 (perhaps unaware of being infected), the two approaches give different epidemic thresholds, with the branching process approximation being more in agreement with simulations.












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