A computational investigation of the ventilation structure and maximum rate of metabolism for a physiologically based pharmacokinetic (PBPK) model of inhaled xylene

DOI10.11145/J.BIOMATH.2019.01.067;MaRDI QIDQ5197816zbMATH OpenFDO

Authors Karen A. Yokley, Jaclyn Ashcraft, Nicholas S. Luke

Publication date 19 September 2019

Published in Biomath (Search for Journal in Brave)

Full work available at URL http://www.biomathforum.org/biomath/index.php/biomath/article/download/j.biomath.2019.01.067/pdf

zbMATH Keywords

PBPK modelingxylene

Mathematics Subject Classification ID

Physiology (general) (92C30) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

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(9)

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• Physiologically based pharmacokinetic models for the transport of trichloroethylene in adipose tissue
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• Experimental data and PBPK modeling quantify antibody interference in PEGylated drug carrier delivery

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