Transcription dynamics of inducible genes modulated by negative regulations

DOI10.1093/IMAMMB/DQT019zbMATH Open1350.92019OpenAlexW1964777188WikidataQ42445240 ScholiaQ42445240MaRDI QIDQ5261613FDOQ5261613

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Publication date: 6 July 2015

Published in: Mathematical Medicine and Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1093/imammb/dqt019

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zbMATH Keywords

nonlinear dynamicsstress-responsive genestranscription repression

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42)

Cited In (12)

• Analytical formula and dynamic profile of mRNA distribution
• The nonlinear dynamics and fluctuations of mRNA levels in cross-talking pathway activated transcription
• Modulation of first-passage time for bursty gene expression via random signals
• Multi-step regulation of transcription kinetics explains the non-linear relation between RNA polymerase II density and mrna expression in dosage compensation
• Autoregulation of transcription and translation: a qualitative analysis
• The dynamics of gene transcription in random environments
• Fluctuations in transcription factor binding can explain the graded and binary responses observed in inducible gene expression
• The dynamics of gene transcription Induced by variation in transcription kinetics
• Negative feedback contributes to the stochastic expression of the interferon-\(\beta\) gene in virus-triggered type I interferon signaling pathways
• Retroactivity effects dependency on the transcription factors binding mechanisms
• The mean and noise of stochastic gene transcription with cell division
• A feedforward loop motif in transcriptional regulation: induction and repression

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