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Testing interaction between treatment and high‐dimensional covariates in randomized clinical trials

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Publication:5280183
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DOI10.1002/bimj.201500194zbMath1369.62291OpenAlexW2532794909WikidataQ39267252 ScholiaQ39267252MaRDI QIDQ5280183

Fernando U. Montoya, Benjamin Dizier, Andrea Callegaro, Bart Spiessens, Hans C. van Houwelingen

Publication date: 20 July 2017

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.201500194


zbMATH Keywords

interactionhigh-dimensional dataclinical trialglobal testpredictive biomarker


Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Reliability and life testing (62N05)


Related Items (1)

LRBmat: a novel gut microbial interaction and individual heterogeneity inference method for colorectal cancer



Cites Work

  • A predictive enrichment procedure to identify potential responders to a new therapy for randomized, comparative controlled clinical studies
  • Estimating Individualized Treatment Rules Using Outcome Weighted Learning
  • A Simple Method for Estimating Interactions Between a Treatment and a Large Number of Covariates
  • Unnamed Item


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