Testing interaction between treatment and high‐dimensional covariates in randomized clinical trials

DOI10.1002/BIMJ.201500194zbMATH Open1369.62291OpenAlexW2532794909WikidataQ39267252 ScholiaQ39267252MaRDI QIDQ5280183FDOQ5280183

Fernando U. Montoya, Benjamin Dizier, Andrea Callegaro, Bart Spiessens, Hans van Houwelingen

Publication date: 20 July 2017

Published in: Biometrical Journal (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1002/bimj.201500194

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zbMATH Keywords

high-dimensional dataclinical trialglobal testinteractionpredictive biomarker

Mathematics Subject Classification ID

Reliability and life testing (62N05) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

• Dynamic prediction in clinical survival analysis
• A Simple Method for Estimating Interactions Between a Treatment and a Large Number of Covariates
• Estimating Individualized Treatment Rules Using Outcome Weighted Learning
• A predictive enrichment procedure to identify potential responders to a new therapy for randomized, comparative controlled clinical studies

Cited In (3)

• LRBmat: a novel gut microbial interaction and individual heterogeneity inference method for colorectal cancer
• Detecting an interaction between treatment and a continuous covariate: a comparison of two approaches
• Two‐stage penalized regression screening to detect biomarker–treatment interactions in randomized clinical trials

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