A Generalized Response Surface Model with Varying Relative Potency for Assessing Drug Interaction

DOI10.1111/J.1541-0420.2006.00579.XMaRDI QIDQ5295352zbMATH OpenOpenAlexWikidataFDO

Authors

Publication date 27 July 2007

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1111/j.1541-0420.2006.00579.x

zbMATH Keywords

additivityantagonismdose response curveinteraction indexsynergy

Mathematics Subject Classification ID

Response surface designs (62K20) Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cites work

• A Biometrics Invited Paper. The Analysis and Selection of Variables in Linear Regression
• Parallel dose-response curves in combination experiments.

Cited in

(13)

• A method for Bayesian monotonic multiple regression
• A model for the interaction of two chemicals
• Nonlinear response surface in the study of interaction analysis of three combination drugs
• A Semiparametric Response Surface Model for Assessing Drug Interaction
• A global model to define the behavior of partial agonists (bell-shaped dose-response inducers) in pharmacological evaluation of activity in the presence of the full agonist
• An extension of the model free test to test synergy in multiple drug combinations
• On dose-response modeling for evaluation of drugs combinations
• Behaviour of the monotone single index model under repeated measurements
• Design and modeling for drug combination experiments with order effects
• Monotonic single-index models to assess drug interactions
• Two-dimensional maximin power designs for combination experiments of drugs
• Compromise design for combination experiment of two drugs
• A mapping-based universal kriging model for order-of-addition experiments in drug combination studies

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Uses Software

• R
• nlmdl

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