Optimal designs for active controlled dose-finding trials with efficacy-toxicity outcomes

DOI10.1093/BIOMET/ASX057MaRDI QIDQ5384555zbMATH OpenOpenAlexWikidataFDO

Authors

Publication date 24 June 2019

Published in Biometrika (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1601.00797

zbMATH Keywords

admissible designequivalence theoremparticle swarm optimizationTchebycheff system

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

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Cited in

(14)

• Optimal designs for dose-response models with linear effects of covariates
• Locally optimal designs for mixed binary and continuous responses
• Optimal designs for dose-escalation trials and individual allocations in cohorts
• Minimax D-optimal designs for multivariate regression models with multi-factors
• Optimal designs for mixed continuous and binary responses with quantitative and qualitative factors
• On optimal designs for nonregular models
• Optimal adaptive designs for acute oral toxicity assessment
• Adaptive Dc-optimal designs for dose finding based on a continuous efficacy endpoint
• Optimal designs for contingent response models with application to toxicity-efficacy studies
• Optimal designs for dose-finding experiments in toxicity studies
• Optimal dose‐finding for efficacy–safety models
• \(D\)-optimal designs for multi-response linear models with two groups
• Optimal designs for quasi-likelihood estimation in active controlled dose-finding trials
• A randomized exchange algorithm for optimal design of multi-response experiments

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