Testing for a treatment-by-stratum interaction in a sequential clinical trial

MaRDI QIDQ5506402zbMATH OpenFDO

Authors B. Yakir, W. J. Hall

Publication date 28 January 2009

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Sequential statistical design (62L05) Sequential statistical analysis (62L10) Optimal stopping in statistics (62L15)

Recommendations

• Testing for Qualitative Interactions between Treatment Effects and Patient Subsets
• A Multivariate Test of Interaction for Use in Clinical Trials
• Testing for Interaction in Studies of Noninferiority
• Sequential Monitoring of Randomization Tests: Stratified Randomization
• Sequential Analysis of Survival Times in Clinical Trials

Cited in

(5)

• Testing for Interaction in Studies of Noninferiority
• A Sequential Significance Test for Treatment by Covariate Interactions
• Robustness of an odds-ratio test in a stratified group sequential trial with a binary outcome measure
• Heterogeneous treatment effects in stratified clinical trials with time‐to‐event endpoints
• Testing synergistic effects for simultaneous exposures with stratified dichotomous response

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