A Diffusion-Reaction Model for the Cellular Uptake of Protein-Bound Ligands

DOI10.1137/0151008MaRDI QIDQ5753776zbMATH OpenOpenAlexFDO

Authors L. Bass, A. McNabb

Publication date 1991

Published in SIAM Journal on Applied Mathematics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1137/0151008

zbMATH Keywords

comparison theoryouter boundaryprotein bindingcell surfacephysiological flowstotal fluxcellular uptakeligandsdiffusion-reaction kineticscarrier proteinsfacilitation of fluxinner boundariesprotein- ligand-ratiosystem of diffusing molecules

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Reaction-diffusion equations (35K57) Nonlinear initial, boundary and initial-boundary value problems for linear parabolic equations (35K60) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Chemically reacting flows (80A32)

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(8)

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• Ussing flux ratio theorems for albumin enhanced fatty acid fluxes across a lipid water interface
• A model for carrier-mediated biological signal transduction based on equilibrium ligand binding theory
• Equilibrium binding of multivalent ligands to cells: Effects of cell and receptor density
• Impact of plasma-protein binding on receptor occupancy: an analytical description
• Moment expressions for some diffusion-reaction problems
• A model of cell surface receptor aggregation
• On the role of diffusible binding partners in modulating the transport and concentration of proteins in tissues

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