Theoretical study of a two-dimensional autocatalytic model for calcium dynamics at the extracellular fluid-bone interface

DOI10.1007/BF02460138MaRDI QIDQ581285zbMATH OpenOpenAlexWikidataFDO

Authors P. Tracqui, Anne-Marie Perault-Staub, Gerard Milhaud, Jean-Francois Staub

Publication date 1987

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/bf02460138

zbMATH Keywords

birhythmicitycalcium metabolismextracellular fluid- bone interfacemultistability propertiesnonlinear substructureorder-two autocatalytic processsecondary nucleation mechanismsself-organized compartmental modelstable periodic regimestemporal behaviourstwo- dimensional model

Mathematics Subject Classification ID

Physiological, cellular and medical topics (92Cxx) Control/observation systems governed by ordinary differential equations (93C15)

Review text

The temporal behaviours of the nonlinear substructure of a self-organized compartmental model of calcium metabolism were investigated. The order- two autocatalytic process included in this simple two-dimensional model is compared to some secondary nucleation mechanisms which should take place at the extracellular fluid-bone interface. The model gives rise to complex dynamic behaviours, and multistability properties, involving up to two stable periodic regimes (birhythmicity), we established in different topological configurations. The bifurcations occurring on the boundaries between regions of different qualitative behaviour have been determined. These properties are discussed in relation to the dynamical behaviour of other two-variable models, especially those including the same nonlinearity.

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Cites work

• Bifurcation formulae derived from center manifold theory
• Classification and unfoldings of degenerate Hopf bifurcations
• Control of mitosis by a continuous biochemical oscillation: synchronization; spatially inhomogeneous oscillations
• scientific article; zbMATH DE number 3743640 (Why is no real title available?)
• scientific article; zbMATH DE number 3566657 (Why is no real title available?)
• Multiple bifurcation problems for chemical reactors
• Nonlinear oscillations, dynamical systems, and bifurcations of vector fields
• Singularities and groups in bifurcation theory. Volume I
• Theoretical study of a two-dimensional autocatalytic model for calcium dynamics at the extracellular fluid-bone interface

Cited in

(8)

• Homoclinic tangencies in an autocatalytic model of interfacial processes at the bone surface
• Mixed-mode oscillation genealogy in a compartmental model of bone mineral metabolism
• Local bifurcations of an enzyme-catalyzed reaction system with cubic rate law
• Analysis of degenerate hopf bifurcations for a nonlinear model of calcium metabolism
• Bifurcation analysis of an enzyme reaction system with general power of autocatalysis
• Theoretical study of a two-dimensional autocatalytic model for calcium dynamics at the extracellular fluid-bone interface
• Stability analysis and Turing pattern of an enzyme-catalyzed reaction model
• Qualitative and quantitative characteristics of modeled and natural oscillatory zoning patterns in calcite

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