On minimising tumoural growth under treatment resistance

DOI10.1016/J.JTBI.2023.111716MaRDI QIDQ6136591zbMATH OpenOpenAlexFDO

Authors Matthias M. Fischer, Nils Blüthgen

Publication date 17 January 2024

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Copyright license Creative Commons Attribution 4.0 International

Full work available at URL https://doi.org/10.1016/j.jtbi.2023.111716

zbMATH Keywords

acquired resistancecancerphenotypic plasticitytargeted therapy

Mathematics Subject Classification ID

Medical applications (general) (92C50)

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Cites work

• A 3-compartment model for chemotherapy of heterogeneous tumor populations
• A stochastic model for the origin and treatment of tumors containing drug-resistant cells
• Drug resistance in cancer chemotherapy as an optimal control problem
• Emergence of anti-cancer drug resistance: exploring the importance of the microenvironmental niche via a spatial model
• Evolution of resistance to anti-cancer therapy during general dosing schedules
• Modeling the effects of space structure and combination therapies on phenotypic heterogeneity and drug resistance in solid tumors
• Populational adaptive evolution, chemotherapeutic resistance and multiple anti-cancer therapies
• Stochastic modeling of cellular colonies with quiescence: an application to drug resistance in cancer
• The impact of cell density and mutations in a model of multidrug resistance in solid tumors

Cited in

(3)

• Tumor containment: a more general mathematical analysis
• Mathematical modeling and dynamic analysis for cancer resistance incorporating persister cells
• Probabilistic analysis of tumor growth inhibition models to support trial design

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