On biological networks capable of robust adaptation in the presence of uncertainties: a linear systems-theoretic approach

DOI10.1016/J.MBS.2023.108984MaRDI QIDQ6157784zbMATH OpenOpenAlexFDO

Authors Priyan Bhattacharya, Karthik Raman, Arun K. Tangirala

Publication date 22 June 2023

Published in Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.mbs.2023.108984

zbMATH Keywords

robustnessinternal model principlevariance minimizationsigned digraphWiener-Kolmogorov filterbiological adaptation

Mathematics Subject Classification ID

Systems biology, networks (92C42) Sensitivity (robustness) (93B35) Linear systems in control theory (93C05)

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Cites work

• scientific article; zbMATH DE number 1404324 (Why is no real title available?)
• Adaptation and regulation with signal detection implies internal model
• An introduction to computational systems biology. Systems-level modelling of cellular networks
• Infinitesimal homeostasis in three-node input-output networks
• Linear systems theory
• Matrices, Digraphs, and Determinants
• Nonlinear Output Regulation
• The structure of infinitesimal homeostasis in input-output networks

Cited in

(6)

• Homeostasis in networks with multiple inputs
• Design principles for the analysis and construction of robustly homeostatic biological networks
• Global stability analysis and robust design of multi-time-scale biological networks under parametric uncertainties
• scientific article; zbMATH DE number 5493348 (Why is no real title available?)
• Design principles for perfect adaptation in biological networks with nonlinear dynamics
• Perfect adaptation of general nonlinear systems

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