Theoretical quantification of the polyvalent binding of nanoparticles coated with peptide-major histocompatibility complex to T cell receptor-nanoclusters
DOI10.1016/J.MBS.2023.108995zbMATH Open1519.92069MaRDI QIDQ6157790FDOQ6157790
Authors: Manuela Pineros-Rodriguez, Louis Richez, Anmar Khadra
Publication date: 22 June 2023
Published in: Mathematical Biosciences (Search for Journal in Brave)
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cooperativitymultiscale modelGibbs free energydissociation constantdensity of bound and triggered TCRsinsertion probabilitypMHC-coated nanoparticlespolyvalent bidingT cell receptorsTCR nanoclusters
Cites Work
- Stochastic effects and bistability in T cell receptor signaling
- The role of low avidity T cells in the protection against type 1 diabetes: a modeling investigation
- Receptor clustering on a cell surface. I. Theory of receptor cross- linking by ligands bearing two chemically identical functional groups
- Receptor clustering on a cell surface. III. Theory of receptor cross- linking by multivalent ligands: Description by ligand states
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