Phase separation reduces cell-to-cell variability of transcriptional bursting

DOI10.1016/j.mbs.2023.109127OpenAlexW4389454325MaRDI QIDQ6194341

Unnamed Author, Zhenquan Zhang, Lijun Hong, Tianshou Zhou, Jia Jun Zhang, Songhao Luo

Publication date: 14 February 2024

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2023.109127

zbMATH Keywords

stochastic gene expressionnoise strengthliquid-liquid phase separationtranscriptional burst

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Biochemistry, molecular biology (92C40) Cell biology (92C37)

Cites Work

• Gene expression noise is affected differentially by feedback in burst frequency and burst size
• Modeling stochastic gene expression: from Markov to non-Markov models
• Using Gene Expression Noise to Understand Gene Regulation
• REMARKS ON THE NONUNIVERSALITY OF BOLTZMANN-GIBBS STATISTICAL MECHANICS
• Information transmission and noise correlation in continuous and bursty signaling systems
• Markovian approaches to modeling intracellular reaction processes with molecular memory
• Univariate Discrete Distributions
• Effect of transcription reinitiation in stochastic gene expression

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