A role of effector CD8^+ T cells against circulating tumor cells cloaked with platelets: insights from a mathematical model

DOI10.1007/S11538-024-01323-YMaRDI QIDQ6572103zbMATH OpenFDO

Authors Khaphetsi Joseph Mahasa, Rachid Ouifki, Lisette De Pillis, Amina Eladdadi

Publication date 15 July 2024

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

zbMATH Keywords

ordinary differential equationsstability analysiscirculating tumor cells\(\text{CD}8^+\) T cellsactivated platelets

Mathematics Subject Classification ID

Qualitative investigation and simulation of ordinary differential equation models (34C60) Cell biology (92C37) Pathology, pathophysiology (92C32)

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Cites work

• A combination therapy of oncolytic viruses and chimeric antigen receptor T cells: a mathematical model proof-of-concept
• A mathematical framework for modelling the metastatic spread of cancer
• A mathematical model for the immune-mediated theory of metastasis
• A mathematical model of cell-mediated immune response to tumor
• A methodology for performing global uncertainty and sensitivity analysis in systems biology
• Implications of immune-mediated metastatic growth on metastatic dormancy, blow-up, early detection, and treatment
• Interactions between the immune system and cancer: A brief review of non-spatial mathematical models
• Mathematical model of tumor-immune surveillance
• Mathematical modelling for the role of CD\(4^+\)T cells in tumor-immune interactions
• Methods for determining key components in a mathematical model for tumor-immune dynamics in multiple myeloma
• Mixed immunotherapy and chemotherapy of tumors: modeling, applications and biological interpretations
• Modeling metastatic tumor evolution, numerical resolution and growth prediction
• Modeling tumor regrowth and immunotherapy
• Nonlinear dynamics of immunogenic tumors: Parameter estimation and global bifurcation analysis

Cited in

(1)

• Tumor shapes effect on metastatic state: a theoretical derivation embedding thermodynamic laws

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