Limits of variance-based sensitivity analysis for non-identifiability testing in high dimensional dynamic models

DOI10.1016/J.AUTOMATICA.2012.05.004MaRDI QIDQ694803zbMATHOpenAlexFDO

Authors Simona Dobre, T. Bastogne, Christophe Profeta, Muriel Barberi-Heyob, Alain Richard

Publication date 13 December 2012

Published in Automatica (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.automatica.2012.05.004

zbMATH Keywords

sensitivity analysisdynamical systemsidentifiabilitynonlinear systemssystems biology

Mathematics Subject Classification ID

Systems biology, networks (92C42) Sensitivity (robustness) (93B35) System identification (93B30) Control/observation systems governed by ordinary differential equations (93C15)

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Cites work

• scientific article; zbMATH DE number 2186466 (Why is no real title available?)
• scientific article; zbMATH DE number 1425054 (Why is no real title available?)
• A Class of Statistics with Asymptotically Normal Distribution
• Automatic Control in Systems Biology
• General foundations of high-dimensional model representations
• Global sensitivity analysis: The primer
• Global sensitivity indices for nonlinear mathematical models and their Monte Carlo estimates
• Identifiability of homogeneous systems using the state isomorphism approach
• Identifiability of linear and nonlinear dynamical systems
• Identification of parametric models from experimental data. Transl. from an upd. French version by the authors, with the help of John Norton
• On global identifiability for arbitrary model parametrizations
• Parameter identifiability of nonlinear systems: The role of initial conditions.
• System identifiability based on the power series expansion of the solution

Cited in

(7)

• Parameter selection and verification techniques based on global sensitivity analysis illustrated for an HIV model
• Parameter subset selection techniques for problems in mathematical biology
• Quantification and reduction of uncertainties in a wind turbine numerical model based on a global sensitivity analysis and a recursive Bayesian inference approach
• Dynamic Bayesian sensitivity analysis of a myocardial metabolic model
• Novel global sensitivity analysis methodology accounting for the crucial role of the distribution of input parameters: application to systems biology models
• A tutorial on Sobol' global sensitivity analysis applied to biological models
• A methodology for performing global uncertainty and sensitivity analysis in systems biology

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