Bystander effects and their implications for clinical radiation therapy: insights from multiscale \textit{in silico} experiments

DOI10.1016/J.JTBI.2016.04.010zbMath1343.92130arXiv1407.0867OpenAlexW1491153233WikidataQ50665188 ScholiaQ50665188MaRDI QIDQ738646

Gibin G. Powathil, Alastair J. Munro, Maciej Swat, Mark A. J. Chaplain

Publication date: 5 September 2016

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1407.0867

zbMATH Keywords

radiation therapycell-cyclemultiscale mathematical modelradiation-induced bystander effects

Mathematics Subject Classification ID

Cell biology (92C37) Computational methods for problems pertaining to biology (92-08)

Related Items (4)

Effects of G2-checkpoint dynamics on low-dose hyper-radiosensitivity ⋮ A reaction-diffusion model for radiation-induced bystander effects ⋮ Predicting radiotherapy patient outcomes with real-time clinical data using mathematical modelling ⋮ Models for the bystander effect in gradient radiation fields: range and signalling type

Cites Work

• Modeling the spatial distribution of chronic tumor hypoxia: implications for experimental and clinical studies
• A model for radiation-induced bystander effects, with allowance for spatial position and the effects of cell turnover
• A model for restriction point control of the mammalian cell cycle
• Modelling the effects of cell-cycle heterogeneity on the response of a solid tumour to chemotherapy: biological insights from a hybrid multiscale cellular automaton model

This page was built for publication: Bystander effects and their implications for clinical radiation therapy: insights from multiscale \textit{in silico} experiments