Regulation of p53 by siRNA in radiation treated cells: Simulation studies

DOI10.2478/v10006-012-0075-9zbMath1283.93041OpenAlexW2039479345MaRDI QIDQ5403413

Roman Jaksik, Andrzej Swierniak, Krzysztof Puszynski

Publication date: 26 March 2014

Published in: International Journal of Applied Mathematics and Computer Science (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.2478/v10006-012-0075-9

zbMATH Keywords

cancer cellscombined therapyintracellular mechanismsp53 signaling pathwaysmall interfering RNA (SIRNA)

Mathematics Subject Classification ID

Related Items (4)

Mathematical analysis of a generalised p53-Mdm2 protein gene expression model ⋮ On p53 revival using system oriented drug dosage design ⋮ Application of bifurcation theory and siRNA-based control signal to restore the proper response of cancer cells to DNA damage ⋮ Building the library of RNA 3D nucleotide conformations using the clustering approach

Cites Work

• Unnamed Item
• Oscillations and bistability in the stochastic model of p53 regulation
• Planning identification experiments for cell signaling pathways: An NFκB case study

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