Models, measurement and inference in epithelial tissue dynamics

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Publication:745142

DOI10.3934/MBE.2015.12.1321zbMATH Open1326.92016arXiv1506.05052OpenAlexW3104128850WikidataQ38699447 ScholiaQ38699447MaRDI QIDQ745142FDOQ745142


Authors: Oliver J. Maclaren, H. M. Byrne, Alexander G. Fletcher, Philip K. Maini Edit this on Wikidata


Publication date: 13 October 2015

Published in: Mathematical Biosciences and Engineering (Search for Journal in Brave)

Abstract: The majority of solid tumours arise in epithelia and therefore much research effort has gone into investigating the growth, renewal and regulation of these tissues. Here we review different mathematical and computational approaches that have been used to model epithelia. We compare different models and describe future challenges that need to be overcome in order to fully exploit new data which present, for the first time, the real possibility for detailed model validation and comparison.


Full work available at URL: https://arxiv.org/abs/1506.05052




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