A method for exploratory repeated-measures analysis applied to a breast-cancer screening study

DOI10.1214/11-AOAS481zbMATH Open1234.62015arXiv1202.6133WikidataQ60499690 ScholiaQ60499690MaRDI QIDQ765989FDOQ765989

Martin Crowder, Susan M. Astley, Jonathan G. James, Fiona Gilbert, Adam R. Brentnall, Matthew G. Wallis, Caroline R. M. Boggis, Stephen W. Duffy, Maureen G. C. Gillan

Publication date: 22 March 2012

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Abstract: When a model may be fitted separately to each individual statistical unit, inspection of the point estimates may help the statistician to understand between-individual variability and to identify possible relationships. However, some information will be lost in such an approach because estimation uncertainty is disregarded. We present a comparative method for exploratory repeated-measures analysis to complement the point estimates that was motivated by and is demonstrated by analysis of data from the CADET II breast-cancer screening study. The approach helped to flag up some unusual reader behavior, to assess differences in performance, and to identify potential random-effects models for further analysis.

Full work available at URL: https://arxiv.org/abs/1202.6133

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zbMATH Keywords

likelihoodclassificationrandom effectsmammogramcomputer-aided detection (CAD)

Mathematics Subject Classification ID

Point estimation (62F10) Estimation in survival analysis and censored data (62N02) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

• The central role of the propensity score in observational studies for causal effects
• Asymptotic Properties of Maximum Likelihood Estimators and Likelihood Ratio Tests Under Nonstandard Conditions
• Nonparametric Maximum Likelihood Estimation of a Mixing Distribution
• Analysis of Repeated Measures
• Statistical inference for exploratory data analysis and model diagnostics
• A method for exploratory repeated-measures analysis applied to a breast-cancer screening study

Cited In (3)

• A method for exploratory repeated-measures analysis applied to a breast-cancer screening study
• A non-parametric regression approach to repeated measures analysis in cancer experiments
• Application of the Principal Stratification Approach to the Faenza Randomized Experiment on Breast Self‐Examination

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