A method for exploratory repeated-measures analysis applied to a breast-cancer screening study

DOI10.1214/11-AOAS481zbMATH Open1234.62015arXiv1202.6133WikidataQ60499690 ScholiaQ60499690MaRDI QIDQ765989FDOQ765989

Authors: Adam R. Brentnall, Stephen W. Duffy, Martin Crowder, Maureen G. C. Gillan, Susan M. Astley, Matthew G. Wallis, Caroline R. M. Boggis, Fiona Gilbert, Jonathan G. James 

Publication date: 22 March 2012

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Abstract: When a model may be fitted separately to each individual statistical unit, inspection of the point estimates may help the statistician to understand between-individual variability and to identify possible relationships. However, some information will be lost in such an approach because estimation uncertainty is disregarded. We present a comparative method for exploratory repeated-measures analysis to complement the point estimates that was motivated by and is demonstrated by analysis of data from the CADET II breast-cancer screening study. The approach helped to flag up some unusual reader behavior, to assess differences in performance, and to identify potential random-effects models for further analysis.

Full work available at URL: https://arxiv.org/abs/1202.6133

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zbMATH Keywords

likelihoodclassificationrandom effectsmammogramcomputer-aided detection (CAD)

Mathematics Subject Classification ID

Point estimation (62F10) Estimation in survival analysis and censored data (62N02) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

• The central role of the propensity score in observational studies for causal effects
• Asymptotic Properties of Maximum Likelihood Estimators and Likelihood Ratio Tests Under Nonstandard Conditions
• Nonparametric Maximum Likelihood Estimation of a Mixing Distribution
• Analysis of Repeated Measures
• Statistical inference for exploratory data analysis and model diagnostics
• A method for exploratory repeated-measures analysis applied to a breast-cancer screening study

Cited In (3)

• A method for exploratory repeated-measures analysis applied to a breast-cancer screening study
• A non-parametric regression approach to repeated measures analysis in cancer experiments
• Application of the Principal Stratification Approach to the Faenza Randomized Experiment on Breast Self‐Examination

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