An analytical study of the number of steady states in gene regulatory networks

DOI10.1016/J.JTBI.2005.03.015MaRDI QIDQ776608zbMATH OpenOpenAlexWikidataFDO

Authors Atsushi Mochizuki

Publication date 9 July 2020

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2005.03.015

zbMATH Keywords

complexityBoolean networksteady statescontinuous modelgene networkdiversity of cell states

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Systems biology, networks (92C42)

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Cites work

• A methodological basis for description and analysis of systems with complex switch-like interactions
• Analysis of continuous-time switching networks
• Dynamics in high-dimensional model gene networks
• Logical identification of all steady states: The concept of feedback loop characteristic states

Cited in

(22)

• Transcriptional autoregulation by phosphorylated and non-phosphorylated KaiC in cyanobacterial circadian rhythms
• Biologically meaningful update rules increase the critical connectivity of generalized Kauffman networks
• Cancer onset and progression: a genome-wide, nonlinear dynamical systems perspective on onconetworks
• Do scale-free regulatory networks allow more expression than random ones?
• Analyzing steady states of dynamics of bio-molecules from the structure of regulatory networks
• Dynamics and control at feedback vertex sets. II: A faithful monitor to determine the diversity of molecular activities in regulatory networks
• Structure of regulatory networks and diversity of gene expression patterns
• Equilibrium switching and mathematical properties of nonlinear interaction networks with concurrent antagonism and self-stimulation
• Piecewise linear and Boolean models of chemical reaction networks
• Comparing different ODE modelling approaches for gene regulatory networks
• Stochastic approach to molecular interactions and computational theory of metabolic and genetic regulations
• Optimization-based approaches to control of probabilistic Boolean networks
• Inferring stable genetic networks from steady-state data
• Mathematical classification of regulatory logics for compound environmental changes
• Optimal control of probabilistic logic networks and its application to real-time pricing of electricity
• Attractor analysis of asynchronous Boolean models of signal transduction networks
• A probabilistic approach to control of complex systems and its application to real-time pricing
• Algorithms for Inference, Analysis and Control of Boolean Networks
• Discrimination of singleton and periodic attractors in Boolean networks
• An Improved Algorithm for Detecting a Singleton Attractor in a Boolean Network Consisting of AND/OR Nodes
• Lebesgue piecewise affine approximation of nonlinear systems
• Reconstruction of transcription-translation dynamics with a model of gene networks

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