Maximum-likelihood estimation of the statistical distribution of Smith- Waterman local sequence similarity scores

DOI10.1007/BF02458620MaRDI QIDQ810409zbMATH OpenOpenAlexWikidataFDO

Authors Richard W. Mott

Publication date 1992

Published in Bulletin of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/bf02458620

zbMATH Keywords

maximum-likelihood estimationDNAgapsSmith-Waterman algorithmprotein sequence similaritiesstatistical significance of sequence similarity scores

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Biochemistry, molecular biology (92C40) Protein sequences, DNA sequences (92D20)

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Cites work

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• scientific article; zbMATH DE number 194302 (Why is no real title available?)
• An accurate approximation to the distribution of the length of the longest matching word between two random DNA sequences
• An extreme value theory for sequence matching
• Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes.
• Stochastic scrabble: large deviations for sequences with scores
• Two moments suffice for Poisson approximations: The Chen-Stein method

Cited in

(8)

• Toward an accurate statistics of gapped alignments
• Maximum likelihood estimates of pairwise rearrangement distances
• Power analysis of database search using multiple scoring matrices
• Estimating the Gumbel scale parameter for local alignment of random sequences by importance sampling with stopping times
• scientific article; zbMATH DE number 434722 (Why is no real title available?)
• scientific article; zbMATH DE number 1746440 (Why is no real title available?)
• scientific article; zbMATH DE number 2130517 (Why is no real title available?)
• Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes.

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