A new latent cure rate marker model for survival data
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Abstract: To address an important risk classification issue that arises in clinical practice, we propose a new mixture model via latent cure rate markers for survival data with a cure fraction. In the proposed model, the latent cure rate markers are modeled via a multinomial logistic regression and patients who share the same cure rate are classified into the same risk group. Compared to available cure rate models, the proposed model fits better to data from a prostate cancer clinical trial. In addition, the proposed model can be used to determine the number of risk groups and to develop a predictive classification algorithm.
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Cites work
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- A New Bayesian Model for Survival Data with a Surviving Fraction
- A new latent cure rate marker model for survival data
- A semiparametric approach for the two-sample comparison of survival times with long-term survivors
- Bayesian Measures of Model Complexity and Fit
- Bayesian analysis of generalized odds-rate hazards models for survival data
- Bayesian survival analysis
- Flexible Cure Rate Modeling Under Latent Activation Schemes
- Interval Mapping of Quantitative Trait Loci for Time‐to‐Event Data with the Proportional Hazards Mixture Cure Model
- Joint Analysis of Time‐to‐Event and Multiple Binary Indicators of Latent Classes
- Latent Class Analysis of Complex Sample Survey Data
- Latent Class Models for Joint Analysis of Longitudinal Biomarker and Event Process Data
- Markov Chain Monte Carlo Convergence Diagnostics: A Comparative Review
- Nonparametric Estimation from Incomplete Observations
- Reversible jump Markov chain Monte Carlo computation and Bayesian model determination
- Survival analysis with long-term survivors
Cited in
(8)- Piecewise linear approximations for cure rate models and associated inferential issues
- The ROC of Cox proportional hazards cure models with application in cancer studies
- On the parameter estimation of Box-Cox transformation cure model
- A new threshold regression model for survival data with a cure fraction
- Bayesian local influence for survival models
- Nonparametric double additive cure survival models: An application to the estimation of the non-linear effect of age at first parenthood on fertility progression
- A flexible cure rate model for spatially correlated survival data based on generalized extreme value distribution and Gaussian process priors
- A new latent cure rate marker model for survival data
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