A new latent cure rate marker model for survival data

DOI10.1214/09-AOAS238zbMATH Open1196.62142arXiv0910.1660OpenAlexW2089601838MaRDI QIDQ985030FDOQ985030

Authors: Sungduk Kim, Yingmei Xi, Ming-Hui Chen 

Publication date: 20 July 2010

Published in: The Annals of Applied Statistics (Search for Journal in Brave)

Abstract: To address an important risk classification issue that arises in clinical practice, we propose a new mixture model via latent cure rate markers for survival data with a cure fraction. In the proposed model, the latent cure rate markers are modeled via a multinomial logistic regression and patients who share the same cure rate are classified into the same risk group. Compared to available cure rate models, the proposed model fits better to data from a prostate cancer clinical trial. In addition, the proposed model can be used to determine the number of risk groups and to develop a predictive classification algorithm.

Full work available at URL: https://arxiv.org/abs/0910.1660

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zbMATH Keywords

Markov chain Monte Carlodeviance information criterion (DIC)logarithm of pseudomarginal likelihood (LPML)PSA recurrence

Mathematics Subject Classification ID

Classification and discrimination; cluster analysis (statistical aspects) (62H30) Applications of statistics to biology and medical sciences; meta analysis (62P10) Medical applications (general) (92C50) Generalized linear models (logistic models) (62J12)

Cites Work

• Bayesian Measures of Model Complexity and Fit
• Title not available (Why is that?)
• Reversible jump Markov chain Monte Carlo computation and Bayesian model determination
• Markov Chain Monte Carlo Convergence Diagnostics: A Comparative Review
• Title not available (Why is that?)
• Nonparametric Estimation from Incomplete Observations
• Title not available (Why is that?)
• Title not available (Why is that?)
• A New Bayesian Model for Survival Data with a Surviving Fraction
• Bayesian survival analysis
• Title not available (Why is that?)
• Title not available (Why is that?)
• Survival analysis with long-term survivors
• Flexible Cure Rate Modeling Under Latent Activation Schemes
• Bayesian analysis of generalized odds-rate hazards models for survival data
• Latent Class Models for Joint Analysis of Longitudinal Biomarker and Event Process Data
• A semiparametric approach for the two-sample comparison of survival times with long-term survivors
• Latent Class Analysis of Complex Sample Survey Data
• A new latent cure rate marker model for survival data
• Interval Mapping of Quantitative Trait Loci for Time‐to‐Event Data with the Proportional Hazards Mixture Cure Model
• Joint Analysis of Time‐to‐Event and Multiple Binary Indicators of Latent Classes

Cited In (8)

• The ROC of Cox proportional hazards cure models with application in cancer studies
• On the parameter estimation of Box-Cox transformation cure model
• A new threshold regression model for survival data with a cure fraction
• Bayesian local influence for survival models
• Nonparametric double additive cure survival models: An application to the estimation of the non-linear effect of age at first parenthood on fertility progression
• A flexible cure rate model for spatially correlated survival data based on generalized extreme value distribution and Gaussian process priors
• A new latent cure rate marker model for survival data
• Piecewise linear approximations for cure rate models and associated inferential issues

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