Self-consistent knowledge-based approach to protein design

DOI10.1007/978-3-540-44827-3_8MaRDI QIDQ3158119zbMATH OpenFDO

Authors Andrea A. Rossi, Cristian Micheletti, Flavio Seno, Amos Maritan

Publication date 20 January 2005

Published in Lecture Notes in Computer Science (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/978-3-540-44827-3_8

Mathematics Subject Classification ID

Theory of languages and software systems (knowledge-based systems, expert systems, etc.) for artificial intelligence (68T35) Biochemistry, molecular biology (92C40)

Recommendations

• Learning effective amino-acid interactions
• Global analysis of protein folding using massively parallel design, synthesis, and testing
• Protein sequence design based on the topology of the native state structure
• A generalized approach for protein design based on the relative entropy
• Highly designable protein structures and inter-monomer interactions

Cited in

(6)

• Protein sequence design based on the topology of the native state structure
• A generalized approach for protein design based on the relative entropy
• Self-consistent ensemble optimization and its implementation for mutation analysis in proteins
• Overcoming the key challenges in de novo protein design: enhancing computational efficiency and incorporating true backbone flexibility
• Global analysis of protein folding using massively parallel design, synthesis, and testing
• An evolution-based model for designing chorismate mutase enzymes

This page was built for publication: Self-consistent knowledge-based approach to protein design

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q3158119)